Plectin (PLEC) - coding DNA reference sequence

(used for mutation description)

(last modified November 27, 2010)


This file was created to facilitate the description of sequence variants in the PLEC gene based on a coding DNA reference sequence following the HGVS recommendations. The sequence was taken from NG_012492.1, covering PLEC transcript NM_000445.3. The gene contains a range of alternative promoters/exon 01 in intron 2, encoding other transcripts; variant-2 (NM_201378.2, exon 01h / protein isoform 1f), variant 3 (NM_201379.1, exon 01g /  isoform 1e), variant-6 (NM_201380.2, exon 01f /  isoform 1), variant-7 (NM_201381.1, exon 01e /  isoform 1d), variant-8 (NM_201382.2, exon 01d /  isoform 1b), variant-10 (NM_201383.1, exon 01c /  isoform 1g), variant-11 (NM_201384.1, exon 01b /  isoform 1a).

Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
                     .         .         .         .    | 02        g.6376
            agtctggctgcggcggcagagctgaagtgagcggagccaccag | gaggcc    c.-1

          .         .         .         .         .         .       g.6436
 ATGTCGGGTGAGGACGCTGAGGTCCGGGCAGTCTCTGAAGATGTCTCCAATGGAAGCAGT       c.60
 M  S  G  E  D  A  E  V  R  A  V  S  E  D  V  S  N  G  S  S         p.20

          .         .         .         .         .         .       g.6496
 GGCTCGCCCAGCCCTGGGGACACACTGCCCTGGAACCTTGGGAAAACGCAGCGGAGCCGG       c.120
 G  S  P  S  P  G  D  T  L  P  W  N  L  G  K  T  Q  R  S  R         p.40

          .         .         .         .         .         .       g.6556
 CGCAGCGGGGGTGGCGCTGGGAGCAACGGGAGTGTCCTGGACCCAGCTGAGCGGGCGGTC       c.180
 R  S  G  G  G  A  G  S  N  G  S  V  L  D  P  A  E  R  A  V         p.60

          .    | 03    .         .         .         .         .    g.43100
 ATTCGCATCGCAG | ATGAGCGGGATCGTGTGCAGAAGAAAACCTTCACCAAGTGGGTCAAC    c.240
 I  R  I  A  D |   E  R  D  R  V  Q  K  K  T  F  T  K  W  V  N      p.80
               ^  intron with 7 alternative promoters/exons 01h-01b

          .      | 04  .         .         .         .         .    g.43550
 AAGCACCTCATCAAG | GCCCAGAGGCACATCAGTGACCTGTATGAAGACCTCCGCGATGGC    c.300
 K  H  L  I  K   | A  Q  R  H  I  S  D  L  Y  E  D  L  R  D  G      p.100

          .         .         .         .      | 05  .         .    g.44518
 CACAACCTCATCTCCCTGCTGGAGGTCCTCTCGGGGGACAGCCTG | CCCCGGGAGAAGGGG    c.360
 H  N  L  I  S  L  L  E  V  L  S  G  D  S  L   | P  R  E  K  G      p.120

          .         .         .         .         .         .       g.44578
 AGGATGCGTTTCCACAAGCTGCAGAATGTCCAGATTGCCCTGGACTACCTCCGGCACCGC       c.420
 R  M  R  F  H  K  L  Q  N  V  Q  I  A  L  D  Y  L  R  H  R         p.140

     | 06    .         .         .         .         .         .    g.44731
 CAG | GTGAAGCTGGTGAACATCAGGAATGATGACATCGCTGACGGCAACCCCAAGCTGACC    c.480
 Q   | V  K  L  V  N  I  R  N  D  D  I  A  D  G  N  P  K  L  T      p.160

          .         .         .       | 07 .         .         .    g.45755
 CTTGGCCTCATCTGGACAATCATTCTGCACTTCCAG | ATCTCAGATATCCAGGTGAGTGGG    c.540
 L  G  L  I  W  T  I  I  L  H  F  Q   | I  S  D  I  Q  V  S  G      p.180

          .         .         .         .         .         .       g.45815
 CAGTCGGAGGACATGACGGCCAAGGAGAAGCTGCTGCTGTGGTCGCAGCGAATGGTGGAG       c.600
 Q  S  E  D  M  T  A  K  E  K  L  L  L  W  S  Q  R  M  V  E         p.200

          .         .         .         .         .         .       g.45875
 GGGTACCAGGGCCTGCGATGCGACAACTTCACCTCCAGCTGGAGAGACGGCCGCCTCTTC       c.660
 G  Y  Q  G  L  R  C  D  N  F  T  S  S  W  R  D  G  R  L  F         p.220

          .         .    | 08    .         .         .         .    g.46469
 AATGCCATCATCCACCGGCACAA | GCCCCTGCTCATCGACATGAACAAGGTGTACCGGCAG    c.720
 N  A  I  I  H  R  H  K  |  P  L  L  I  D  M  N  K  V  Y  R  Q      p.240

          .         .         .         .         .         .       g.46529
 ACCAACCTGGAGAACCTGGACCAGGCCTTCTCTGTGGCGGAGCGGGACCTGGGAGTGACG       c.780
 T  N  L  E  N  L  D  Q  A  F  S  V  A  E  R  D  L  G  V  T         p.260

          .          | 09        .         .         .         .    g.46669
 CGGCTCCTGGACCCTGAGG | ACGTGGATGTCCCTCAGCCCGACGAGAAGTCCATCATCACC    c.840
 R  L  L  D  P  E  D |   V  D  V  P  Q  P  D  E  K  S  I  I  T      p.280

          .         .         .         .         .         .       g.46729
 TACGTCTCGTCGCTGTATGACGCCATGCCCCGCGTGCCGGACGTGCAGGATGGGGTGAGG       c.900
 Y  V  S  S  L  Y  D  A  M  P  R  V  P  D  V  Q  D  G  V  R         p.300

        | 10 .         .         .         .         .         .    g.46870
 GCCAAC | GAGCTGCAGCTGCGCTGGCAGGAGTACCGGGAGCTGGTGCTGCTGCTGCTTCAG    c.960
 A  N   | E  L  Q  L  R  W  Q  E  Y  R  E  L  V  L  L  L  L  Q      p.320

          .         .         .         .         .         .       g.46930
 TGGATGCGACACCACACGGCCGCCTTTGAGGAACGCAGGTTCCCCTCCAGCTTCGAGGAG       c.1020
 W  M  R  H  H  T  A  A  F  E  E  R  R  F  P  S  S  F  E  E         p.340

        | 11 .         .         .         .         .         .    g.47069
 ATTGAG | ATCCTGTGGTCTCAGTTCCTGAAGTTTAAGGAGATGGAGCTACCAGCCAAGGAG    c.1080
 I  E   | I  L  W  S  Q  F  L  K  F  K  E  M  E  L  P  A  K  E      p.360

          .         .         .         .   | 12     .         .    g.47318
 GCCGACAAGAACAGGTCCAAGGGCATCTACCAATCCCTGGAG | GGAGCGGTGCAAGCAGGC    c.1140
 A  D  K  N  R  S  K  G  I  Y  Q  S  L  E   | G  A  V  Q  A  G      p.380

          .         .         .         .         .         .       g.47378
 CAGCTCAAGGTGCCCCCTGGCTACCACCCGCTGGATGTGGAGAAGGAGTGGGGCAAGCTG       c.1200
 Q  L  K  V  P  P  G  Y  H  P  L  D  V  E  K  E  W  G  K  L         p.400

          .         .         .         .         . | 13       .    g.47664
 CACGTGGCCATCCTGGAGCGGGAGAAGCAGCTCCGCAGCGAGTTTGAGAG | GCTGGAGTGT    c.1260
 H  V  A  I  L  E  R  E  K  Q  L  R  S  E  F  E  R  |  L  E  C      p.420

          .         .         .         .         .         .       g.47724
 CTTCAGCGCATCGTGACCAAGCTGCAGATGGAGGCGGGGCTGTGTGAGGAGCAGCTGAAC       c.1320
 L  Q  R  I  V  T  K  L  Q  M  E  A  G  L  C  E  E  Q  L  N         p.440

          .         .     | 14   .         .         .         .    g.48430
 CAGGCCGACGCCCTGCTGCAGTCG | GATGTCCGGCTGCTGGCTGCAGGCAAAGTGCCACAG    c.1380
 Q  A  D  A  L  L  Q  S   | D  V  R  L  L  A  A  G  K  V  P  Q      p.460

          .         .         .         .         .         .       g.48490
 CGGGCGGGGGAGGTGGAACGGGACTTGGACAAGGCGGATAGCATGATCCGGCTGCTCTTC       c.1440
 R  A  G  E  V  E  R  D  L  D  K  A  D  S  M  I  R  L  L  F         p.480

          .         .         .         .         .          | 15    g.48635
 AACGACGTGCAGACCCTCAAGGATGGACGGCACCCGCAGGGCGAGCAGATGTACCGCAG | G    c.1500
 N  D  V  Q  T  L  K  D  G  R  H  P  Q  G  E  Q  M  Y  R  R  |      p.500

          .         .         .         .         .         .       g.48695
 GTGTACCGTCTGCACGAGCGCCTGGTAGCCATCCGCACCGAGTACAACCTACGGCTGAAG       c.1560
 V  Y  R  L  H  E  R  L  V  A  I  R  T  E  Y  N  L  R  L  K         p.520

          .         .         .         .         .         .       g.48755
 GCAGGCGTGGCGGCCCCTGCAACCCAGGTGGCCCAGGTGACTCTGCAGAGTGTGCAGAGG       c.1620
 A  G  V  A  A  P  A  T  Q  V  A  Q  V  T  L  Q  S  V  Q  R         p.540

          .         .         .         .         .         .       g.48815
 CGCCCCGAGCTGGAGGACTCCACTCTGCGCTACCTGCAGGACCTGCTGGCCTGGGTGGAG       c.1680
 R  P  E  L  E  D  S  T  L  R  Y  L  Q  D  L  L  A  W  V  E         p.560

          .         .         .         .         .         .       g.48875
 GAGAACCAGCACCGTGTGGATGGCGCTGAGTGGGGTGTGGACCTGCCCAGCGTGGAGGCG       c.1740
 E  N  Q  H  R  V  D  G  A  E  W  G  V  D  L  P  S  V  E  A         p.580

          .         .         .         .         .         .       g.48935
 CAGCTGGGCAGCCACCGAGGCCTGCACCAGTCCATCGAAGAATTCCGGGCCAAGATCGAG       c.1800
 Q  L  G  S  H  R  G  L  H  Q  S  I  E  E  F  R  A  K  I  E         p.600

          .         | 16         .         .         .         .    g.49075
 CGGGCACGGAGTGACGAG | GGCCAGCTCTCCCCCGCCACCCGGGGTGCCTACCGTGACTGC    c.1860
 R  A  R  S  D  E   | G  Q  L  S  P  A  T  R  G  A  Y  R  D  C      p.620

          .         .         .       | 17 .         .         .    g.49208
 CTGGGTCGGCTGGACCTGCAGTACGCCAAGCTGCTG | AACTCCTCCAAGGCCCGCCTCAGG    c.1920
 L  G  R  L  D  L  Q  Y  A  K  L  L   | N  S  S  K  A  R  L  R      p.640

          .         .         .         .         .         .       g.49268
 TCCCTGGAGAGCTTGCACAGCTTTGTGGCAGCCGCCACTAAGGAGCTAATGTGGCTGAAT       c.1980
 S  L  E  S  L  H  S  F  V  A  A  A  T  K  E  L  M  W  L  N         p.660

          .         .         .         .         .         .       g.49328
 GAGAAGGAGGAGGAGGAGGTGGGCTTCGACTGGAGCGACCGCAACACCAACATGACCGCC       c.2040
 E  K  E  E  E  E  V  G  F  D  W  S  D  R  N  T  N  M  T  A         p.680

          .         | 18         .         .         .         .    g.49553
 AAGAAGGAGAGCTACTCG | GCGCTGATGCGGGAGCTGGAGCTGAAGGAGAAGAAGATCAAG    c.2100
 K  K  E  S  Y  S   | A  L  M  R  E  L  E  L  K  E  K  K  I  K      p.700

          .         .         .         .         .         .       g.49613
 GAGCTCCAAAATGCTGGGGACCGGCTGCTGCGGGAGGACCACCCGGCCCGGCCCACGGTG       c.2160
 E  L  Q  N  A  G  D  R  L  L  R  E  D  H  P  A  R  P  T  V         p.720

     | 19    .         .         .         .         .         .    g.49770
 GAG | TCCTTCCAGGCGGCCCTGCAGACGCAGTGGAGCTGGATGCTACAGCTGTGCTGCTGT    c.2220
 E   | S  F  Q  A  A  L  Q  T  Q  W  S  W  M  L  Q  L  C  C  C      p.740

          .         .         .          | 20        .         .    g.50107
 ATCGAGGCACACCTGAAGGAGAACGCTGCCTACTTTCAG | TTCTTCTCAGATGTGCGGGAG    c.2280
 I  E  A  H  L  K  E  N  A  A  Y  F  Q   | F  F  S  D  V  R  E      p.760

          .         .         .         .         .         .       g.50167
 GCCGAGGGGCAGTTGCAGAAGCTGCAGGAGGCACTGCGTAGGAAATACAGTTGTGATCGC       c.2340
 A  E  G  Q  L  Q  K  L  Q  E  A  L  R  R  K  Y  S  C  D  R         p.780

          .         .         .         .      | 21  .         .    g.51224
 TCCGCCACCGTCACCCGGCTGGAGGACCTGCTGCAGGATGCCCAG | GACGAGAAGGAACAG    c.2400
 S  A  T  V  T  R  L  E  D  L  L  Q  D  A  Q   | D  E  K  E  Q      p.800

          .         .         .         .         .         .       g.51284
 CTGAACGAGTACAAGGGCCACCTCTCAGGCCTGGCCAAGCGGGCCAAGGCCGTCGTGCAG       c.2460
 L  N  E  Y  K  G  H  L  S  G  L  A  K  R  A  K  A  V  V  Q         p.820

          .         .         .         .         .         .       g.51344
 CTGAAGCCCCGCCACCCAGCCCACCCCATGCGGGGCCGCCTGCCCCTGCTGGCCGTGTGC       c.2520
 L  K  P  R  H  P  A  H  P  M  R  G  R  L  P  L  L  A  V  C         p.840

          .         | 22         .         .         .         .    g.51489
 GACTATAAGCAGGTGGAG | GTGACTGTGCACAAGGGTGACGAGTGCCAGCTGGTGGGCCCT    c.2580
 D  Y  K  Q  V  E   | V  T  V  H  K  G  D  E  C  Q  L  V  G  P      p.860

          .         .         .         .         .         .       g.51549
 GCACAGCCGTCCCACTGGAAGGTGCTCAGCAGCTCCGGCAGCGAGGCCGCCGTGCCCTCC       c.2640
 A  Q  P  S  H  W  K  V  L  S  S  S  G  S  E  A  A  V  P  S         p.880

          .         .         .         .         .    | 23    .    g.51690
 GTGTGCTTCCTGGTGCCCCCGCCCAACCAGGAGGCCCAGGAGGCCGTCACCAG | GCTGGAG    c.2700
 V  C  F  L  V  P  P  P  N  Q  E  A  Q  E  A  V  T  R  |  L  E      p.900

          .         .         .         .         .         .       g.51750
 GCCCAGCACCAGGCCCTGGTCACGCTGTGGCACCAGTTGCACGTGGACATGAAGAGCCTT       c.2760
 A  Q  H  Q  A  L  V  T  L  W  H  Q  L  H  V  D  M  K  S  L         p.920

          .         .         .         .         .         .       g.51810
 CTGGCCTGGCAGAGCCTTCGCCGCGACGTGCAGCTCATCCGCTCCTGGTCCCTGGCCACG       c.2820
 L  A  W  Q  S  L  R  R  D  V  Q  L  I  R  S  W  S  L  A  T         p.940

  | 24       .         .         .         .         .         .    g.51976
  | TTCCGCACCCTGAAGCCAGAGGAGCAGCGCCAAGCCCTGCACAGCCTGGAGCTGCACTAC    c.2880
  | F  R  T  L  K  P  E  E  Q  R  Q  A  L  H  S  L  E  L  H  Y      p.960

          .         .         .         .         .         .       g.52036
 CAGGCCTTCCTGCGGGACAGCCAGGACGCGGGCGGCTTCGGACCCGAGGACCGGCTGATG       c.2940
 Q  A  F  L  R  D  S  Q  D  A  G  G  F  G  P  E  D  R  L  M         p.980

          .         .         .         .         .         .       g.52096
 GCTGAGCGCGAGTACGGCTCCTGCAGCCACCACTACCAGCAGCTGCTGCAGAGCCTGGAA       c.3000
 A  E  R  E  Y  G  S  C  S  H  H  Y  Q  Q  L  L  Q  S  L  E         p.1000

      | 25   .         .         .         .         .         .    g.52230
 CAGG | GTGCACAGGAAGAGTCTCGCTGCCAGCGCTGCATCTCCGAGCTCAAAGACATCCGG    c.3060
 Q  G |   A  Q  E  E  S  R  C  Q  R  C  I  S  E  L  K  D  I  R      p.1020

          .         .         .         .         .         .       g.52290
 CTGCAGCTGGAGGCCTGTGAGACGCGCACCGTGCACCGCCTGCGGCTGCCGCTGGACAAA       c.3120
 L  Q  L  E  A  C  E  T  R  T  V  H  R  L  R  L  P  L  D  K         p.1040

          .         .         .         .   | 26     .         .    g.52482
 GAGCCGGCACGGGAGTGTGCCCAGCGCATCGCCGAGCAGCAG | AAGGCACAGGCAGAGGTG    c.3180
 E  P  A  R  E  C  A  Q  R  I  A  E  Q  Q   | K  A  Q  A  E  V      p.1060

          .         .         .         .         .         .       g.52542
 GAGGGGCTGGGCAAGGGGGTCGCCCGGCTCTCTGCCGAGGCCGAGAAGGTCTTGGCCCTA       c.3240
 E  G  L  G  K  G  V  A  R  L  S  A  E  A  E  K  V  L  A  L         p.1080

          .         .         .         .         .         .       g.52602
 CCAGAGCCATCGCCTGCGGCCCCCACGCTGCGCTCGGAGCTGGAGCTGACGCTGGGCAAG       c.3300
 P  E  P  S  P  A  A  P  T  L  R  S  E  L  E  L  T  L  G  K         p.1100

          .         .         .         .  | 27      .         .    g.53772
 CTGGAGCAGGTCCGCAGCCTGTCTGCCATCTACCTGGAGAA | GCTCAAGACCATCAGCCTG    c.3360
 L  E  Q  V  R  S  L  S  A  I  Y  L  E  K  |  L  K  T  I  S  L      p.1120

          .         .         .         .         .         .       g.53832
 GTGATCCGCGGCACGCAGGGGGCCGAGGAGGTGCTCAGGGCCCACGAGGAGCAGCTCAAG       c.3420
 V  I  R  G  T  Q  G  A  E  E  V  L  R  A  H  E  E  Q  L  K         p.1140

          .         .         .         .         .         .       g.53892
 GAGGCCCAGGCCGTGCCGGCCACCCTCCCGGAGCTCGAGGCCACCAAGGCCTCTCTGAAG       c.3480
 E  A  Q  A  V  P  A  T  L  P  E  L  E  A  T  K  A  S  L  K         p.1160

  | 28       .         .         .         .         .         .    g.54039
  | AAGCTGCGGGCCCAGGCCGAGGCACAGCAGCCCACGTTCGACGCCCTGCGGGATGAGCTG    c.3540
  | K  L  R  A  Q  A  E  A  Q  Q  P  T  F  D  A  L  R  D  E  L      p.1180

          .         .         .         .         .         .       g.54099
 CGGGGGGCACAGGAGGTGGGGGAGCGACTGCAGCAGCGGCACGGGGAGCGGGACGTGGAG       c.3600
 R  G  A  Q  E  V  G  E  R  L  Q  Q  R  H  G  E  R  D  V  E         p.1200

          .         .         .         .         .         .       g.54159
 GTGGAGCGCTGGCGGGAGCGGGTCGCCCAGTTGCTTGAGCGCTGGCAGGCTGTGCTGGCC       c.3660
 V  E  R  W  R  E  R  V  A  Q  L  L  E  R  W  Q  A  V  L  A         p.1220

          .         .         .         .         .         .       g.54219
 CAGACCGACGTGCGGCAGCGCGAGCTCGAGCAACTGGGCCGCCAGCTGCGTTACTACCGC       c.3720
 Q  T  D  V  R  Q  R  E  L  E  Q  L  G  R  Q  L  R  Y  Y  R         p.1240

          .         .         .         .         .         .       g.54279
 GAGAGTGCAGACCCCTTGGGCGCCTGGCTGCAGGACGCCAGGCGGCGGCAGGAGCAGATC       c.3780
 E  S  A  D  P  L  G  A  W  L  Q  D  A  R  R  R  Q  E  Q  I         p.1260

          .         .         .         .         .        | 29.    g.54413
 CAGGCCATGCCGCTGGCCGACAGCCAGGCTGTGCGGGAGCAGCTGCGGCAGGAGCAG | GCC    c.3840
 Q  A  M  P  L  A  D  S  Q  A  V  R  E  Q  L  R  Q  E  Q   | A      p.1280

          .         .         .         .         .         .       g.54473
 CTGCTGGAGGAGATCGAGCGCCACGGCGAGAAGGTCGAGGAGTGCCAGAGGTTTGCGAAA       c.3900
 L  L  E  E  I  E  R  H  G  E  K  V  E  E  C  Q  R  F  A  K         p.1300

          .         .  | 30      .         .         .         .    g.54703
 CAGTACATCAACGCCATCAAG | GACTATGAACTCCAGCTGGTGACGTACAAGGCGCAGCTT    c.3960
 Q  Y  I  N  A  I  K   | D  Y  E  L  Q  L  V  T  Y  K  A  Q  L      p.1320

          .         .         .         .         .         .       g.54763
 GAGCCGGTGGCCTCCCCGGCCAAGAAGCCCAAGGTCCAGTCGGGATCAGAGAGTGTCATC       c.4020
 E  P  V  A  S  P  A  K  K  P  K  V  Q  S  G  S  E  S  V  I         p.1340

        | 31 .         .         .         .         .         .    g.54917
 CAGGAG | TACGTGGACCTGCGTACGCACTACAGCGAGCTGACCACACTGACGAGCCAGTAC    c.4080
 Q  E   | Y  V  D  L  R  T  H  Y  S  E  L  T  T  L  T  S  Q  Y      p.1360

          .         .         .         .      | 32  .         .    g.55876
 ATCAAGTTCATCAGCGAGACTCTGCGGCGCATGGAGGAGGAGGAG | AGGCTGGCTGAGCAG    c.4140
 I  K  F  I  S  E  T  L  R  R  M  E  E  E  E   | R  L  A  E  Q      p.1380

          .         .         .         .         .         .       g.55936
 CAGCGGGCAGAGGAGCGCGAGCGGCTGGCCGAGGTGGAGGCCGCGCTGGAGAAGCAGCGG       c.4200
 Q  R  A  E  E  R  E  R  L  A  E  V  E  A  A  L  E  K  Q  R         p.1400

          .         .         .         .         .         .       g.55996
 CAGCTGGCCGAGGCGCACGCCCAGGCAAAGGCACAGGCGGAGCGGGAGGCGAAGGAGCTG       c.4260
 Q  L  A  E  A  H  A  Q  A  K  A  Q  A  E  R  E  A  K  E  L         p.1420

          .         .         .         .         .         .       g.56056
 CAGCAGCGCATGCAGGAGGAGGTGGTGCGGCGGGAGGAGGCGGCGGTGGACGCGCAGCAG       c.4320
 Q  Q  R  M  Q  E  E  V  V  R  R  E  E  A  A  V  D  A  Q  Q         p.1440

          .         .         .         .         .         .       g.56116
 CAGAAGCGCAGCATTCAGGAGGAGCTGCAGCAGCTGCGGCAGAGCTCGGAGGCGGAGATC       c.4380
 Q  K  R  S  I  Q  E  E  L  Q  Q  L  R  Q  S  S  E  A  E  I         p.1460

          .         .         .         .         .         .       g.56176
 CAGGCCAAGGCCCGGCAGGCAGAGGCGGCTGAGCGCAGCCGGCTGCGCATCGAGGAGGAG       c.4440
 Q  A  K  A  R  Q  A  E  A  A  E  R  S  R  L  R  I  E  E  E         p.1480

          .         .         .         .         .         .       g.56236
 ATCCGCGTGGTGCGCCTGCAGTTGGAGGCCACCGAGCGCCAGCGTGGCGGGGCTGAGGGG       c.4500
 I  R  V  V  R  L  Q  L  E  A  T  E  R  Q  R  G  G  A  E  G         p.1500

          .         .         .         .         .         .       g.56296
 GAGCTGCAGGCACTGCGTGCACGGGCGGAGGAGGCTGAGGCACAAAAGCGACAGGCGCAG       c.4560
 E  L  Q  A  L  R  A  R  A  E  E  A  E  A  Q  K  R  Q  A  Q         p.1520

          .         .         .         .         .         .       g.56356
 GAGGAGGCCGAGCGCTTGCGGAGGCAGGTGCAGGACGAGAGCCAGCGTAAGCGGCAGGCG       c.4620
 E  E  A  E  R  L  R  R  Q  V  Q  D  E  S  Q  R  K  R  Q  A         p.1540

          .         .         .         .         .         .       g.56416
 GAGGTGGAGCTGGCCTCGCGCGTGAAGGCCGAGGCCGAGGCGGCGCGCGAGAAGCAGCGG       c.4680
 E  V  E  L  A  S  R  V  K  A  E  A  E  A  A  R  E  K  Q  R         p.1560

          .         .         .         .         .         .       g.56476
 GCCCTGCAGGCCCTGGAGGAGCTGCGGCTGCAGGCGGAGGAGGCGGAGCGGCGCCTGCGG       c.4740
 A  L  Q  A  L  E  E  L  R  L  Q  A  E  E  A  E  R  R  L  R         p.1580

          .         .         .         .         .         .       g.56536
 CAGGCCGAGGTGGAGCGAGCGCGGCAGGTACAGGTGGCCCTGGAGACGGCGCAGCGCAGT       c.4800
 Q  A  E  V  E  R  A  R  Q  V  Q  V  A  L  E  T  A  Q  R  S         p.1600

          .         .         .         .         .         .       g.56596
 GCAGAGGCGGAGCTGCAGAGCAAACGCGCCTCCTTCGCCGAGAAGACGGCACAGCTGGAG       c.4860
 A  E  A  E  L  Q  S  K  R  A  S  F  A  E  K  T  A  Q  L  E         p.1620

          .         .         .         .         .         .       g.56656
 CGCTCCCTGCAGGAGGAACACGTGGCTGTGGCACAGCTGCGGGAGGAGGCTGAGCGGCGG       c.4920
 R  S  L  Q  E  E  H  V  A  V  A  Q  L  R  E  E  A  E  R  R         p.1640

          .         .         .         .         .         .       g.56716
 GCACAGCAGCAGGCCGAGGCCGAGCGGGCGCGCGAGGAGGCAGAGCGGGAGCTGGAGCGC       c.4980
 A  Q  Q  Q  A  E  A  E  R  A  R  E  E  A  E  R  E  L  E  R         p.1660

          .         .         .         .         .         .       g.56776
 TGGCAGCTCAAGGCCAACGAGGCGCTACGGCTGCGGCTGCAGGCGGAGGAGGTGGCGCAG       c.5040
 W  Q  L  K  A  N  E  A  L  R  L  R  L  Q  A  E  E  V  A  Q         p.1680

          .         .         .         .         .         .       g.56836
 CAGAAGAGCCTGGCGCAGGCCGAGGCTGAGAAGCAGAAGGAGGAGGCGGAGCGCGAGGCG       c.5100
 Q  K  S  L  A  Q  A  E  A  E  K  Q  K  E  E  A  E  R  E  A         p.1700

          .         .         .         .         .         .       g.56896
 CGGCGGCGCGGCAAGGCGGAGGAGCAGGCCGTCCGGCAGCGGGAGCTGGCTGAACAAGAG       c.5160
 R  R  R  G  K  A  E  E  Q  A  V  R  Q  R  E  L  A  E  Q  E         p.1720

          .         .         .         .         .         .       g.56956
 CTGGAGAAGCAGCGGCAGCTGGCGGAAGGCACCGCGCAGCAGCGCCTGGCCGCGGAGCAG       c.5220
 L  E  K  Q  R  Q  L  A  E  G  T  A  Q  Q  R  L  A  A  E  Q         p.1740

          .         .         .         .         .         .       g.57016
 GAGTTGATCCGGCTGCGGGCCGAGACGGAGCAGGGGGAGCAGCAGCGGCAGCTGCTGGAG       c.5280
 E  L  I  R  L  R  A  E  T  E  Q  G  E  Q  Q  R  Q  L  L  E         p.1760

          .         .         .         .         .         .       g.57076
 GAGGAGCTGGCCCGGCTGCAGCGTGAGGCGGCTGCAGCCACGCAGAAACGGCAGGAGCTG       c.5340
 E  E  L  A  R  L  Q  R  E  A  A  A  A  T  Q  K  R  Q  E  L         p.1780

          .         .         .         .         .         .       g.57136
 GAAGCCGAGCTGGCCAAGGTGCGGGCCGAGATGGAGGTGCTGCTGGCCAGCAAGGCGAGG       c.5400
 E  A  E  L  A  K  V  R  A  E  M  E  V  L  L  A  S  K  A  R         p.1800

          .         .         .         .         .         .       g.57196
 GCTGAGGAGGAGTCGCGCTCCACCAGCGAGAAGTCCAAGCAGAGGCTGGAGGCCGAGGCC       c.5460
 A  E  E  E  S  R  S  T  S  E  K  S  K  Q  R  L  E  A  E  A         p.1820

          .         .         .         .         .         .       g.57256
 GGCCGGTTCCGCGAGCTGGCCGAGGAGGCCGCCCGCCTGCGTGCCCTGGCGGAAGAGGCC       c.5520
 G  R  F  R  E  L  A  E  E  A  A  R  L  R  A  L  A  E  E  A         p.1840

          .         .         .         .         .         .       g.57316
 AAGCGGCAGCGGCAGCTGGCCGAGGAAGACGCGGCGCGGCAGCGGGCCGAGGCGGAGCGG       c.5580
 K  R  Q  R  Q  L  A  E  E  D  A  A  R  Q  R  A  E  A  E  R         p.1860

          .         .         .         .         .         .       g.57376
 GTGCTTGCGGAGAAGCTGGCCGCCATCGGCGAGGCCACGCGGCTCAAGACGGAGGCGGAG       c.5640
 V  L  A  E  K  L  A  A  I  G  E  A  T  R  L  K  T  E  A  E         p.1880

          .         .         .         .         .         .       g.57436
 ATCGCGCTCAAGGAGAAGGAGGCGGAGAACGAGCGCCTGCGGCGGCTGGCGGAGGACGAG       c.5700
 I  A  L  K  E  K  E  A  E  N  E  R  L  R  R  L  A  E  D  E         p.1900

          .         .         .         .         .         .       g.57496
 GCCTTCCAGCGGCGGCGGCTGGAGGAGCAGGCCGCGCAACACAAGGCTGACATCGAGGAG       c.5760
 A  F  Q  R  R  R  L  E  E  Q  A  A  Q  H  K  A  D  I  E  E         p.1920

          .         .         .         .         .         .       g.57556
 CGCCTGGCCCAGCTGCGCAAGGCATCGGACAGCGAGCTGGAGCGGCAGAAGGGGCTGGTG       c.5820
 R  L  A  Q  L  R  K  A  S  D  S  E  L  E  R  Q  K  G  L  V         p.1940

          .         .         .         .         .         .       g.57616
 GAGGACACGCTGAGGCAGCGGCGGCAGGTGGAGGAGGAGATCCTGGCGCTGAAGGCGAGC       c.5880
 E  D  T  L  R  Q  R  R  Q  V  E  E  E  I  L  A  L  K  A  S         p.1960

          .         .         .         .         .         .       g.57676
 TTCGAGAAGGCGGCCGCTGGCAAGGCGGAGCTGGAGCTGGAGCTGGGACGCATCCGCAGC       c.5940
 F  E  K  A  A  A  G  K  A  E  L  E  L  E  L  G  R  I  R  S         p.1980

          .         .         .         .         .         .       g.57736
 AACGCGGAGGACACGCTGCGCAGCAAGGAGCAGGCCGAGCTGGAGGCTGCGAGGCAGCGG       c.6000
 N  A  E  D  T  L  R  S  K  E  Q  A  E  L  E  A  A  R  Q  R         p.2000

          .         .         .         .         .         .       g.57796
 CAGCTGGCGGCGGAGGAGGAGCGGCGGCGCCGTGAGGCTGAGGAGCGCGTGCAGAAGAGC       c.6060
 Q  L  A  A  E  E  E  R  R  R  R  E  A  E  E  R  V  Q  K  S         p.2020

          .         .         .         .         .         .       g.57856
 CTGGCGGCCGAGGAGGAGGCCGCACGGCAGCGGAAGGCGGCGCTGGAGGAAGTCGAGCGG       c.6120
 L  A  A  E  E  E  A  A  R  Q  R  K  A  A  L  E  E  V  E  R         p.2040

          .         .         .         .         .         .       g.57916
 CTGAAAGCCAAGGTGGAGGAGGCGCGGCGCCTGCGGGAGCGAGCGGAGCAGGAGTCGGCG       c.6180
 L  K  A  K  V  E  E  A  R  R  L  R  E  R  A  E  Q  E  S  A         p.2060

          .         .         .         .         .         .       g.57976
 CGGCAGCTGCAGCTGGCCCAGGAGGCCGCCCAGAAGCGGCTGCAGGCGGAAGAGAAGGCA       c.6240
 R  Q  L  Q  L  A  Q  E  A  A  Q  K  R  L  Q  A  E  E  K  A         p.2080

          .         .         .         .         .         .       g.58036
 CACGCCTTCGCGGTGCAGCAGAAGGAGCAGGAGCTACAGCAGACGCTGCAGCAGGAGCAG       c.6300
 H  A  F  A  V  Q  Q  K  E  Q  E  L  Q  Q  T  L  Q  Q  E  Q         p.2100

          .         .         .         .         .         .       g.58096
 AGCGTGCTGGACCAGCTGCGCGGCGAGGCGGAGGCGGCCCGGCGGGCGGCTGAGGAGGCG       c.6360
 S  V  L  D  Q  L  R  G  E  A  E  A  A  R  R  A  A  E  E  A         p.2120

          .         .         .         .         .         .       g.58156
 GAGGAGGCCCGGGTGCAGGCGGAGCGTGAGGCGGCGCAGTCCCGGCGGCAGGTGGAAGAG       c.6420
 E  E  A  R  V  Q  A  E  R  E  A  A  Q  S  R  R  Q  V  E  E         p.2140

          .         .         .         .         .         .       g.58216
 GCCGAGCGGCTGAAGCAGTCGGCAGAGGAGCAGGCACAGGCCCGGGCTCAGGCACAGGCG       c.6480
 A  E  R  L  K  Q  S  A  E  E  Q  A  Q  A  R  A  Q  A  Q  A         p.2160

          .         .         .         .         .         .       g.58276
 GCTGCAGAGAAGCTGCGCAAGGAGGCCGAGCAAGAGGCGGCGCGGCGGGCACAGGCGGAG       c.6540
 A  A  E  K  L  R  K  E  A  E  Q  E  A  A  R  R  A  Q  A  E         p.2180

          .         .         .         .         .         .       g.58336
 CAGGCGGCCCTGCGGCAGAAGCAGGCAGCTGACGCGGAGATGGAGAAGCATAAGAAATTC       c.6600
 Q  A  A  L  R  Q  K  Q  A  A  D  A  E  M  E  K  H  K  K  F         p.2200

          .         .         .         .         .         .       g.58396
 GCCGAGCAGACGCTGCGGCAGAAGGCGCAGGTGGAGCAGGAGCTGACAACACTGCGGCTG       c.6660
 A  E  Q  T  L  R  Q  K  A  Q  V  E  Q  E  L  T  T  L  R  L         p.2220

          .         .         .         .         .         .       g.58456
 CAGCTGGAGGAGACCGACCACCAGAAGAACCTGCTGGACGAGGAGCTGCAGCGGCTGAAG       c.6720
 Q  L  E  E  T  D  H  Q  K  N  L  L  D  E  E  L  Q  R  L  K         p.2240

          .         .         .         .         .         .       g.58516
 GCGGAGGCCACGGAGGCCGCACGCCAGCGCAGCCAGGTGGAGGAGGAGCTCTTCTCGGTG       c.6780
 A  E  A  T  E  A  A  R  Q  R  S  Q  V  E  E  E  L  F  S  V         p.2260

          .         .         .         .         .         .       g.58576
 CGCGTGCAGATGGAGGAGCTGAGCAAGCTCAAGGCACGCATCGAGGCTGAGAACCGCGCA       c.6840
 R  V  Q  M  E  E  L  S  K  L  K  A  R  I  E  A  E  N  R  A         p.2280

          .         .         .         .         .         .       g.58636
 CTCATCTTGCGTGACAAGGACAATACGCAGCGCTTCCTGCAGGAGGAGGCTGAGAAGATG       c.6900
 L  I  L  R  D  K  D  N  T  Q  R  F  L  Q  E  E  A  E  K  M         p.2300

          .         .         .         .         .         .       g.58696
 AAGCAGGTGGCGGAGGAGGCCGCGCGGCTGAGTGTGGCGGCCCAAGAGGCTGCGCGACTG       c.6960
 K  Q  V  A  E  E  A  A  R  L  S  V  A  A  Q  E  A  A  R  L         p.2320

          .         .         .         .         .         .       g.58756
 CGGCAGCTGGCAGAGGAGGACCTGGCACAGCAGCGGGCCTTGGCAGAGAAGATGCTCAAG       c.7020
 R  Q  L  A  E  E  D  L  A  Q  Q  R  A  L  A  E  K  M  L  K         p.2340

          .         .         .         .         .         .       g.58816
 GAGAAGATGCAGGCGGTGCAGGAGGCCACGCGACTCAAGGCTGAGGCGGAACTGCTGCAG       c.7080
 E  K  M  Q  A  V  Q  E  A  T  R  L  K  A  E  A  E  L  L  Q         p.2360

          .         .         .         .         .         .       g.58876
 CAGCAGAAGGAGCTTGCGCAGGAGCAGGCGCGGCGGCTGCAGGAGGACAAGGAGCAGATG       c.7140
 Q  Q  K  E  L  A  Q  E  Q  A  R  R  L  Q  E  D  K  E  Q  M         p.2380

          .         .         .         .         .         .       g.58936
 GCGCAGCAGCTGGCGGAGGAGACGCAGGGCTTCCAGCGGACGCTGGAGGCCGAGCGGCAG       c.7200
 A  Q  Q  L  A  E  E  T  Q  G  F  Q  R  T  L  E  A  E  R  Q         p.2400

          .         .         .         .         .         .       g.58996
 CGGCAGCTGGAGATGAGCGCTGAGGCTGAGCGCCTCAAGCTGCGTGTGGCCGAGATGAGC       c.7260
 R  Q  L  E  M  S  A  E  A  E  R  L  K  L  R  V  A  E  M  S         p.2420

          .         .         .         .         .         .       g.59056
 CGAGCCCAGGCCCGCGCTGAGGAGGACGCCCAGCGCTTCCGGAAGCAGGCGGAGGAGATC       c.7320
 R  A  Q  A  R  A  E  E  D  A  Q  R  F  R  K  Q  A  E  E  I         p.2440

          .         .         .         .         .         .       g.59116
 GGTGAGAAGCTGCACCGCACGGAGCTCGCCACCCAGGAGAAGGTGACCCTGGTGCAGACA       c.7380
 G  E  K  L  H  R  T  E  L  A  T  Q  E  K  V  T  L  V  Q  T         p.2460

          .         .         .         .         .         .       g.59176
 CTGGAGATCCAGCGACAGCAGAGTGACCATGATGCCGAGCGCCTGCGGGAGGCCATCGCT       c.7440
 L  E  I  Q  R  Q  Q  S  D  H  D  A  E  R  L  R  E  A  I  A         p.2480

          .         .         .         .         .         .       g.59236
 GAGCTGGAGCGTGAGAAGGAGAAGCTCCAACAGGAGGCCAAACTGCTGCAGCTCAAGTCT       c.7500
 E  L  E  R  E  K  E  K  L  Q  Q  E  A  K  L  L  Q  L  K  S         p.2500

        | 33 .         .         .         .         .         .    g.59404
 GAGGAG | ATGCAGACGGTGCAGCAGGAGCAGCTGCTGCAGGAGACGCAGGCCCTGCAGCAA    c.7560
 E  E   | M  Q  T  V  Q  Q  E  Q  L  L  Q  E  T  Q  A  L  Q  Q      p.2520

          .         .         .         .         .         .       g.59464
 AGCTTCCTCTCTGAAAAGGACAGCCTGCTACAGCGGGAGCGCTTCATCGAGCAGGAGAAG       c.7620
 S  F  L  S  E  K  D  S  L  L  Q  R  E  R  F  I  E  Q  E  K         p.2540

          .         .         .         .         .         .       g.59524
 GCCAAGCTGGAGCAGCTCTTCCAGGACGAGGTGGCCAAGGCACAGCAGCTGCGTGAGGAG       c.7680
 A  K  L  E  Q  L  F  Q  D  E  V  A  K  A  Q  Q  L  R  E  E         p.2560

          .         .         .         .         .         .       g.59584
 CAGCAGCGGCAGCAGCAGCAGATGGAGCAGGAACGGCAGCGGCTGGTGGCCAGCATGGAG       c.7740
 Q  Q  R  Q  Q  Q  Q  M  E  Q  E  R  Q  R  L  V  A  S  M  E         p.2580

          .         .         .         .         .         .       g.59644
 GAGGCGCGGCGGCGGCAGCATGAGGCCGAGGAGGGCGTGCGGCGCAAGCAGGAGGAGCTG       c.7800
 E  A  R  R  R  Q  H  E  A  E  E  G  V  R  R  K  Q  E  E  L         p.2600

          .         .         .         .         .         .       g.59704
 CAGCAGCTGGAGCAGCAGCGGCGGCAGCAGGAGGAGCTGCTGGCTGAGGAGAACCAGAGG       c.7860
 Q  Q  L  E  Q  Q  R  R  Q  Q  E  E  L  L  A  E  E  N  Q  R         p.2620

          .         .         .         .         .         .       g.59764
 CTGCGTGAGCAGCTGCAGCTCCTGGAGGAGCAGCACCGGGCCGCGCTGGCGCACTCAGAG       c.7920
 L  R  E  Q  L  Q  L  L  E  E  Q  H  R  A  A  L  A  H  S  E         p.2640

          .         .         .         .         .         .       g.59824
 GAGGTCACTGCCTCGCAGGTGGCTGCCACAAAGACCCTGCCCAATGGCCGGGATGCACTT       c.7980
 E  V  T  A  S  Q  V  A  A  T  K  T  L  P  N  G  R  D  A  L         p.2660

          .         .         .         .         .         .       g.59884
 GATGGCCCCGCGGCAGAGGCAGAGCCGGAGCACAGCTTCGATGGCCTGCGGCGGAAGGTG       c.8040
 D  G  P  A  A  E  A  E  P  E  H  S  F  D  G  L  R  R  K  V         p.2680

          .         .         .         .         .         .       g.59944
 TCAGCTCAGAGGCTGCAGGAGGCCGGCATCCTGAGTGCGGAGGAGCTGCAGCGGTTGGCG       c.8100
 S  A  Q  R  L  Q  E  A  G  I  L  S  A  E  E  L  Q  R  L  A         p.2700

          .         .         .         .         .         .       g.60004
 CAGGGCCACACCACGGTGGACGAGCTCGCACGGCGGGAAGACGTGCGCCACTACCTGCAG       c.8160
 Q  G  H  T  T  V  D  E  L  A  R  R  E  D  V  R  H  Y  L  Q         p.2720

          .         .         .         .         .         .       g.60064
 GGCCGCAGCAGTATCGCAGGGCTGTTGCTGAAGGCCACCAATGAGAAGCTGAGTGTTTAC       c.8220
 G  R  S  S  I  A  G  L  L  L  K  A  T  N  E  K  L  S  V  Y         p.2740

          .         .         .         .         .         .       g.60124
 GCCGCCCTGCAGAGGCAGCTGCTGAGTCCCGGCACGGCCCTCATCCTGCTGGAGGCGCAG       c.8280
 A  A  L  Q  R  Q  L  L  S  P  G  T  A  L  I  L  L  E  A  Q         p.2760

          .         .         .         .         .         .       g.60184
 GCGGCCTCAGGCTTCCTGCTGGACCCTGTGCGGAACCGGCGGCTGACCGTCAACGAGGCT       c.8340
 A  A  S  G  F  L  L  D  P  V  R  N  R  R  L  T  V  N  E  A         p.2780

          .         .         .         .         .         .       g.60244
 GTGAAGGAGGGTGTGGTGGGCCCCGAGCTGCACCACAAGCTGCTGTCGGCCGAGCGCGCC       c.8400
 V  K  E  G  V  V  G  P  E  L  H  H  K  L  L  S  A  E  R  A         p.2800

          .         .         .         .         .         .       g.60304
 GTCACTGGCTACAAGGACCCCTACACTGGCCAGCAGATCTCTCTCTTCCAAGCCATGCAG       c.8460
 V  T  G  Y  K  D  P  Y  T  G  Q  Q  I  S  L  F  Q  A  M  Q         p.2820

          .         .         .         .         .         .       g.60364
 AAGGGCCTCATCGTCCGGGAGCACGGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGC       c.8520
 K  G  L  I  V  R  E  H  G  I  R  L  L  E  A  Q  I  A  T  G         p.2840

          .         .         .         .         .         .       g.60424
 GGCGTTATCGACCCCGTGCACAGCCACCGCGTGCCCGTGGACGTGGCCTACCGGCGCGGC       c.8580
 G  V  I  D  P  V  H  S  H  R  V  P  V  D  V  A  Y  R  R  G         p.2860

          .         .         .         .         .         .       g.60484
 TACTTCGACGAGGAGATGAACCGCGTCCTGGCGGACCCCAGCGACGACACCAAGGGCTTC       c.8640
 Y  F  D  E  E  M  N  R  V  L  A  D  P  S  D  D  T  K  G  F         p.2880

          .         .         .         .         .         .       g.60544
 TTTGACCCCAACACGCACGAGAACCTCACGTACCTGCAGCTACTGGAGCGCTGCGTGGAG       c.8700
 F  D  P  N  T  H  E  N  L  T  Y  L  Q  L  L  E  R  C  V  E         p.2900

          .         .         .         .         .         .       g.60604
 GACCCCGAGACGGGCCTGTGCCTTCTGCCACTCACGGATAAGGCTGCCAAGGGCGGGGAG       c.8760
 D  P  E  T  G  L  C  L  L  P  L  T  D  K  A  A  K  G  G  E         p.2920

          .         .         .         .         .         .       g.60664
 CTGGTCTACACTGACTCCGAGGCCCGGGACGTCTTTGAGAAGGCCACCGTGTCTGCGCCG       c.8820
 L  V  Y  T  D  S  E  A  R  D  V  F  E  K  A  T  V  S  A  P         p.2940

          .         .         .         .         .         .       g.60724
 TTCGGCAAGTTCCAGGGCAAGACGGTGACCATTTGGGAGATCATCAACTCGGAATACTTC       c.8880
 F  G  K  F  Q  G  K  T  V  T  I  W  E  I  I  N  S  E  Y  F         p.2960

          .         .         .         .         .         .       g.60784
 ACGGCAGAGCAGCGGCGGGACCTGCTGCGGCAGTTCCGCACGGGCCGGATCACAGTGGAG       c.8940
 T  A  E  Q  R  R  D  L  L  R  Q  F  R  T  G  R  I  T  V  E         p.2980

          .         .         .         .         .         .       g.60844
 AAGATCATCAAGATCATCATCACGGTGGTGGAGGAGCAGGAGCAGAAGGGCCGGCTTTGC       c.9000
 K  I  I  K  I  I  I  T  V  V  E  E  Q  E  Q  K  G  R  L  C         p.3000

          .         .         .         .         .         .       g.60904
 TTTGAGGGCCTGCGCAGCCTGGTGCCAGCCGCCGAGCTGCTGGAGAGCAGGGTCATCGAC       c.9060
 F  E  G  L  R  S  L  V  P  A  A  E  L  L  E  S  R  V  I  D         p.3020

          .         .         .         .         .         .       g.60964
 CGCGAGCTCTACCAGCAGCTGCAGCGAGGTGAGCGCTCTGTGCGAGACGTAGCCGAGGTG       c.9120
 R  E  L  Y  Q  Q  L  Q  R  G  E  R  S  V  R  D  V  A  E  V         p.3040

          .         .         .         .         .         .       g.61024
 GACACTGTGCGGCGGGCTCTCCGGGGTGCCAACGTCATCGCGGGTGTATGGCTGGAGGAG       c.9180
 D  T  V  R  R  A  L  R  G  A  N  V  I  A  G  V  W  L  E  E         p.3060

          .         .         .         .         .         .       g.61084
 GCGGGGCAGAAGCTGAGTATCTACAATGCCCTGAAGAAAGACCTGCTGCCATCCGACATG       c.9240
 A  G  Q  K  L  S  I  Y  N  A  L  K  K  D  L  L  P  S  D  M         p.3080

          .         .         .         .         .         .       g.61144
 GCCGTGGCCCTGTTGGAAGCCCAGGCCGGCACCGGGCACATCATCGACCCCGCCACCAGC       c.9300
 A  V  A  L  L  E  A  Q  A  G  T  G  H  I  I  D  P  A  T  S         p.3100

          .         .         .         .         .         .       g.61204
 GCCCGGCTGACCGTGGACGAGGCAGTGCGTGCTGGCCTGGTGGGCCCCGAGTTTCATGAG       c.9360
 A  R  L  T  V  D  E  A  V  R  A  G  L  V  G  P  E  F  H  E         p.3120

          .         .         .         .         .         .       g.61264
 AAGCTGCTATCAGCCGAGAAGGCTGTGACAGGGTACAGGGACCCCTACACAGGGCAGAGC       c.9420
 K  L  L  S  A  E  K  A  V  T  G  Y  R  D  P  Y  T  G  Q  S         p.3140

          .         .         .         .         .         .       g.61324
 GTCTCCCTGTTCCAGGCCCTGAAGAAGGGCCTCATTCCCCGGGAGCAGGGCCTGCGCCTG       c.9480
 V  S  L  F  Q  A  L  K  K  G  L  I  P  R  E  Q  G  L  R  L         p.3160

          .         .         .         .         .         .       g.61384
 TTGGACGCCCAGCTGTCCACGGGCGGCATCGTGGACCCCAGCAAGAGCCACCGCGTGCCC       c.9540
 L  D  A  Q  L  S  T  G  G  I  V  D  P  S  K  S  H  R  V  P         p.3180

          .         .         .         .         .         .       g.61444
 CTGGATGTCGCCTGCGCCCGAGGCTGCCTGGATGAGGAGACCAGCAGGGCCCTGTCGGCA       c.9600
 L  D  V  A  C  A  R  G  C  L  D  E  E  T  S  R  A  L  S  A         p.3200

          .         .         .         .         .         .       g.61504
 CCAAGGGCCGACGCCAAGGCCTACAGTGACCCCAGCACAGGGGAGCCGGCCACCTACGGC       c.9660
 P  R  A  D  A  K  A  Y  S  D  P  S  T  G  E  P  A  T  Y  G         p.3220

          .         .         .         .         .         .       g.61564
 GAGCTCCAGCAGCGGTGCCGGCCCGACCAGCTGACCGGGCTGAGCCTGCTGCCGCTCTCA       c.9720
 E  L  Q  Q  R  C  R  P  D  Q  L  T  G  L  S  L  L  P  L  S         p.3240

          .         .         .         .         .         .       g.61624
 GAAAAGGCTGCTCGGGCCCGGCAGGAGGAGCTCTACTCAGAGCTGCAGGCCCGTGAGACC       c.9780
 E  K  A  A  R  A  R  Q  E  E  L  Y  S  E  L  Q  A  R  E  T         p.3260

          .         .         .         .         .         .       g.61684
 TTTGAAAAGACCCCGGTTGAGGTCCCCGTGGGTGGCTTCAAGGGCAGGACGGTGACGGTG       c.9840
 F  E  K  T  P  V  E  V  P  V  G  G  F  K  G  R  T  V  T  V         p.3280

          .         .         .         .         .         .       g.61744
 TGGGAGCTCATCAGCTCTGAGTACTTCACTGCGGAGCAGCGGCAGGAGCTGTTGCGTCAG       c.9900
 W  E  L  I  S  S  E  Y  F  T  A  E  Q  R  Q  E  L  L  R  Q         p.3300

          .         .         .         .         .         .       g.61804
 TTCCGCACGGGCAAGGTCACCGTGGAGAAGGTCATCAAGATTCTCATTACCATCGTGGAG       c.9960
 F  R  T  G  K  V  T  V  E  K  V  I  K  I  L  I  T  I  V  E         p.3320

          .         .         .         .         .         .       g.61864
 GAGGTGGAGACCCTGCGGCAGGAGAGGCTGTCCTTCAGCGGCCTCCGTGCCCCTGTGCCA       c.10020
 E  V  E  T  L  R  Q  E  R  L  S  F  S  G  L  R  A  P  V  P         p.3340

          .         .         .         .         .         .       g.61924
 GCCAGCGAGCTCCTGGCTTCCGGGGTCCTCAGCAGAGCCCAGTTTGAGCAGCTCAAGGAC       c.10080
 A  S  E  L  L  A  S  G  V  L  S  R  A  Q  F  E  Q  L  K  D         p.3360

          .         .         .         .         .         .       g.61984
 GGCAAGACGACGGTCAAGGACCTTTCGGAGCTGGGCTCCGTGCGGACGCTGCTGCAGGGC       c.10140
 G  K  T  T  V  K  D  L  S  E  L  G  S  V  R  T  L  L  Q  G         p.3380

          .         .         .         .         .         .       g.62044
 AGTGGCTGCCTCGCCGGCATCTACCTGGAGGACACCAAGGAGAAGGTGTCCATCTACGAG       c.10200
 S  G  C  L  A  G  I  Y  L  E  D  T  K  E  K  V  S  I  Y  E         p.3400

          .         .         .         .         .         .       g.62104
 GCCATGCGCCGGGGCCTGCTGAGAGCCACAACGGCTGCGCTCCTGCTGGAGGCGCAGGCG       c.10260
 A  M  R  R  G  L  L  R  A  T  T  A  A  L  L  L  E  A  Q  A         p.3420

          .         .         .         .         .         .       g.62164
 GCCACTGGCTTCCTGGTGGACCCCGTGCGGAACCAGCGCCTGTATGTCCACGAGGCCGTG       c.10320
 A  T  G  F  L  V  D  P  V  R  N  Q  R  L  Y  V  H  E  A  V         p.3440

          .         .         .         .         .         .       g.62224
 AAGGCGGGCGTGGTGGGCCCCGAGCTTCACGAGCAGCTGCTGTCTGCCGAGAAGGCCGTC       c.10380
 K  A  G  V  V  G  P  E  L  H  E  Q  L  L  S  A  E  K  A  V         p.3460

          .         .         .         .         .         .       g.62284
 ACCGGCTACAGAGACCCCTACTCGGGCAGCACCATCTCCCTCTTCCAGGCCATGCAGAAG       c.10440
 T  G  Y  R  D  P  Y  S  G  S  T  I  S  L  F  Q  A  M  Q  K         p.3480

          .         .         .         .         .         .       g.62344
 GGCCTGGTTCTCCGGCAGCACGGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGCGGC       c.10500
 G  L  V  L  R  Q  H  G  I  R  L  L  E  A  Q  I  A  T  G  G         p.3500

          .         .         .         .         .         .       g.62404
 ATCATCGACCCCGTGCACAGCCACCGCGTGCCTGTGGACGTGGCCTACCAGCGCGGCTAC       c.10560
 I  I  D  P  V  H  S  H  R  V  P  V  D  V  A  Y  Q  R  G  Y         p.3520

          .         .         .         .         .         .       g.62464
 TTCAGTGAGGAGATGAACCGCGTCCTGGCGGACCCCAGCGACGACACCAAGGGCTTCTTT       c.10620
 F  S  E  E  M  N  R  V  L  A  D  P  S  D  D  T  K  G  F  F         p.3540

          .         .         .         .         .         .       g.62524
 GACCCCAACACGCATGAGAACCTCACGTACAGGCAGCTGCTGGAGCGGTGCGTGGAGGAC       c.10680
 D  P  N  T  H  E  N  L  T  Y  R  Q  L  L  E  R  C  V  E  D         p.3560

          .         .         .         .         .         .       g.62584
 CCCGAGACGGGCTTGCGCCTTCTGCCACTGAAAGGGGCGGAGAAGGCTGAGGTGGTGGAG       c.10740
 P  E  T  G  L  R  L  L  P  L  K  G  A  E  K  A  E  V  V  E         p.3580

          .         .         .         .         .         .       g.62644
 ACCACGCAGGTGTACACTGAGGAGGAGACAAGAAGGGCATTTGAAGAGACACAGATCGAC       c.10800
 T  T  Q  V  Y  T  E  E  E  T  R  R  A  F  E  E  T  Q  I  D         p.3600

          .         .         .         .         .         .       g.62704
 ATTCCCGGCGGCGGCAGCCACGGCGGCTCCACCATGTCCCTGTGGGAGGTGATGCAGTCG       c.10860
 I  P  G  G  G  S  H  G  G  S  T  M  S  L  W  E  V  M  Q  S         p.3620

          .         .         .         .         .         .       g.62764
 GACCTGATCCCCGAGGAGCAGCGGGCCCAGCTGATGGCTGACTTCCAGGCCGGCCGGGTG       c.10920
 D  L  I  P  E  E  Q  R  A  Q  L  M  A  D  F  Q  A  G  R  V         p.3640

          .         .         .         .         .         .       g.62824
 ACCAAGGAACGCATGATCATCATCATCATCGAGATCATTGAGAAGACAGAGATCATCCGC       c.10980
 T  K  E  R  M  I  I  I  I  I  E  I  I  E  K  T  E  I  I  R         p.3660

          .         .         .         .         .         .       g.62884
 CAGCAGGGTCTGGCCTCCTACGACTACGTGCGCCGCCGCCTCACGGCTGAGGACCTGTTC       c.11040
 Q  Q  G  L  A  S  Y  D  Y  V  R  R  R  L  T  A  E  D  L  F         p.3680

          .         .         .         .         .         .       g.62944
 GAGGCTCGGATCATCTCTCTCGAGACCTACAACCTGCTCCGGGAGGGCACCAGGAGCCTC       c.11100
 E  A  R  I  I  S  L  E  T  Y  N  L  L  R  E  G  T  R  S  L         p.3700

          .         .         .         .         .         .       g.63004
 CGTGAGGCTCTCGAGGCGGAGTCCGCCTGGTGCTACCTCTATGGCACGGGCTCCGTGGCT       c.11160
 R  E  A  L  E  A  E  S  A  W  C  Y  L  Y  G  T  G  S  V  A         p.3720

          .         .         .         .         .         .       g.63064
 GGTGTCTACCTGCCCGGTTCCAGGCAGACACTGAGCATCTACCAGGCTCTCAAGAAAGGG       c.11220
 G  V  Y  L  P  G  S  R  Q  T  L  S  I  Y  Q  A  L  K  K  G         p.3740

          .         .         .         .         .         .       g.63124
 CTGCTGAGTGCCGAGGTGGCCCGCCTGCTGCTGGAGGCACAGGCAGCCACAGGCTTCCTG       c.11280
 L  L  S  A  E  V  A  R  L  L  L  E  A  Q  A  A  T  G  F  L         p.3760

          .         .         .         .         .         .       g.63184
 CTGGACCCGGTGAAGGGGGAGCGGCTGACTGTGGATGAGGCTGTGCGGAAGGGCCTCGTG       c.11340
 L  D  P  V  K  G  E  R  L  T  V  D  E  A  V  R  K  G  L  V         p.3780

          .         .         .         .         .         .       g.63244
 GGGCCCGAGCTGCACGACCGCCTGCTCTCGGCTGAGCGGGCGGTCACCGGCTACCGTGAC       c.11400
 G  P  E  L  H  D  R  L  L  S  A  E  R  A  V  T  G  Y  R  D         p.3800

          .         .         .         .         .         .       g.63304
 CCCTACACCGAGCAGACCATCTCGCTCTTCCAGGCCATGAAGAAGGAGCTGATCCCTACT       c.11460
 P  Y  T  E  Q  T  I  S  L  F  Q  A  M  K  K  E  L  I  P  T         p.3820

          .         .         .         .         .         .       g.63364
 GAGGAGGCCCTGCGGCTGCTGGATGCCCAGCTGGCCACCGGCGGCATCGTGGACCCCCGC       c.11520
 E  E  A  L  R  L  L  D  A  Q  L  A  T  G  G  I  V  D  P  R         p.3840

          .         .         .         .         .         .       g.63424
 CTGGGCTTCCACCTTCCCCTGGAGGTGGCTTACCAGCGTGGCTACCTCAACAAGGACACG       c.11580
 L  G  F  H  L  P  L  E  V  A  Y  Q  R  G  Y  L  N  K  D  T         p.3860

          .         .         .         .         .         .       g.63484
 CACGACCAGCTGTCAGAGCCCAGCGAGGTGCGCAGCTACGTGGACCCGTCCACCGACGAG       c.11640
 H  D  Q  L  S  E  P  S  E  V  R  S  Y  V  D  P  S  T  D  E         p.3880

          .         .         .         .         .         .       g.63544
 CGCCTCAGCTACACGCAGCTGCTCAGGCGGTGCCGTCGTGACGACGGCACCGGCCAGCTG       c.11700
 R  L  S  Y  T  Q  L  L  R  R  C  R  R  D  D  G  T  G  Q  L         p.3900

          .         .         .         .         .         .       g.63604
 CTCCTGCCACTGTCGGACGCCCGCAAGCTGACCTTCCGTGGCCTGCGGAAGCAGATCACC       c.11760
 L  L  P  L  S  D  A  R  K  L  T  F  R  G  L  R  K  Q  I  T         p.3920

          .         .         .         .         .         .       g.63664
 ATGGAGGAGCTGGTGCGCTCGCAGGTCATGGACGAGGCCACGGCGCTGCAGCTGCGGGAG       c.11820
 M  E  E  L  V  R  S  Q  V  M  D  E  A  T  A  L  Q  L  R  E         p.3940

          .         .         .         .         .         .       g.63724
 GGCCTGACCTCCATCGAGGAGGTCACCAAGAACTTGCAGAAGTTCCTGGAAGGCACCAGC       c.11880
 G  L  T  S  I  E  E  V  T  K  N  L  Q  K  F  L  E  G  T  S         p.3960

          .         .         .         .         .         .       g.63784
 TGCATCGCTGGTGTCTTCGTGGACGCCACCAAGGAACGGCTCTCGGTGTACCAGGCCATG       c.11940
 C  I  A  G  V  F  V  D  A  T  K  E  R  L  S  V  Y  Q  A  M         p.3980

          .         .         .         .         .         .       g.63844
 AAGAAGGGCATCATCCGCCCCGGCACAGCCTTTGAGCTCCTGGAGGCGCAGGCGGCCACC       c.12000
 K  K  G  I  I  R  P  G  T  A  F  E  L  L  E  A  Q  A  A  T         p.4000

          .         .         .         .         .         .       g.63904
 GGTTACGTCATCGACCCCATCAAGGGACTGAAGCTGACGGTGGAGGAGGCTGTGCGTATG       c.12060
 G  Y  V  I  D  P  I  K  G  L  K  L  T  V  E  E  A  V  R  M         p.4020

          .         .         .         .         .         .       g.63964
 GGCATTGTGGGCCCCGAGTTCAAGGACAAGCTGCTGTCGGCCGAGCGCGCCGTCACTGGG       c.12120
 G  I  V  G  P  E  F  K  D  K  L  L  S  A  E  R  A  V  T  G         p.4040

          .         .         .         .         .         .       g.64024
 TACAAGGACCCCTACTCTGGGAAGCTCATCTCCCTCTTCCAGGCCATGAAGAAGGGCCTG       c.12180
 Y  K  D  P  Y  S  G  K  L  I  S  L  F  Q  A  M  K  K  G  L         p.4060

          .         .         .         .         .         .       g.64084
 ATCCTGAAGGACCATGGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGCGGCATCATC       c.12240
 I  L  K  D  H  G  I  R  L  L  E  A  Q  I  A  T  G  G  I  I         p.4080

          .         .         .         .         .         .       g.64144
 GACCCTGAGGAGAGCCACCGGCTGCCCGTGGAGGTGGCCTACAAGCGCGGCCTCTTCGAT       c.12300
 D  P  E  E  S  H  R  L  P  V  E  V  A  Y  K  R  G  L  F  D         p.4100

          .         .         .         .         .         .       g.64204
 GAGGAGATGAACGAGATCCTGACCGACCCCTCGGACGACACCAAGGGCTTCTTTGACCCT       c.12360
 E  E  M  N  E  I  L  T  D  P  S  D  D  T  K  G  F  F  D  P         p.4120

          .         .         .         .         .         .       g.64264
 AACACGGAGGAGAACCTCACCTACCTGCAGCTGATGGAGCGTTGTATCACTGACCCCCAG       c.12420
 N  T  E  E  N  L  T  Y  L  Q  L  M  E  R  C  I  T  D  P  Q         p.4140

          .         .         .         .         .         .       g.64324
 ACGGGCCTGTGTCTCTTGCCGCTGAAGGAGAAGAAGCGGGAGCGGAAGACGTCCTCCAAG       c.12480
 T  G  L  C  L  L  P  L  K  E  K  K  R  E  R  K  T  S  S  K         p.4160

          .         .         .         .         .         .       g.64384
 TCCTCCGTGCGCAAGCGCCGAGTGGTCATCGTGGACCCCGAGACGGGCAAGGAGATGTCA       c.12540
 S  S  V  R  K  R  R  V  V  I  V  D  P  E  T  G  K  E  M  S         p.4180

          .         .         .         .         .         .       g.64444
 GTGTACGAGGCCTACCGCAAGGGCCTGATTGACCACCAGACGTACCTGGAGCTGTCCGAG       c.12600
 V  Y  E  A  Y  R  K  G  L  I  D  H  Q  T  Y  L  E  L  S  E         p.4200

          .         .         .         .         .         .       g.64504
 CAGGAGTGCGAGTGGGAGGAGATCACCATCTCCTCCTCGGACGGCGTGGTCAAGTCCATG       c.12660
 Q  E  C  E  W  E  E  I  T  I  S  S  S  D  G  V  V  K  S  M         p.4220

          .         .         .         .         .         .       g.64564
 ATCATCGACCGCCGCTCCGGGCGCCAGTACGACATCGATGATGCCATCGCCAAGAACCTC       c.12720
 I  I  D  R  R  S  G  R  Q  Y  D  I  D  D  A  I  A  K  N  L         p.4240

          .         .         .         .         .         .       g.64624
 ATCGACCGCTCGGCACTGGACCAGTACCGCGCCGGCACGCTCTCCATCACCGAGTTCGCC       c.12780
 I  D  R  S  A  L  D  Q  Y  R  A  G  T  L  S  I  T  E  F  A         p.4260

          .         .         .         .         .         .       g.64684
 GACATGCTCTCGGGCAACGCCGGTGGTTTCCGCTCCCGTTCCTCCTCGGTGGGATCCTCC       c.12840
 D  M  L  S  G  N  A  G  G  F  R  S  R  S  S  S  V  G  S  S         p.4280

          .         .         .         .         .         .       g.64744
 TCCTCCTACCCCATCAGCCCCGCCGTCTCCAGGACCCAGCTGGCCTCCTGGTCAGACCCC       c.12900
 S  S  Y  P  I  S  P  A  V  S  R  T  Q  L  A  S  W  S  D  P         p.4300

          .         .         .         .         .         .       g.64804
 ACTGAGGAGACGGGCCCCGTGGCTGGCATCCTGGACACGGAGACGCTGGAGAAGGTGTCC       c.12960
 T  E  E  T  G  P  V  A  G  I  L  D  T  E  T  L  E  K  V  S         p.4320

          .         .         .         .         .         .       g.64864
 ATCACCGAGGCCATGCACCGGAACCTGGTGGATAACATCACGGGGCAGCGGCTGCTGGAG       c.13020
 I  T  E  A  M  H  R  N  L  V  D  N  I  T  G  Q  R  L  L  E         p.4340

          .         .         .         .         .         .       g.64924
 GCGCAGGCCTGCACCGGGGGCATCATCGACCCCAGCACCGGTGAGCGCTTCCCTGTCACC       c.13080
 A  Q  A  C  T  G  G  I  I  D  P  S  T  G  E  R  F  P  V  T         p.4360

          .         .         .         .         .         .       g.64984
 GACGCCGTCAACAAGGGCCTGGTGGACAAGATCATGGTGGACCGCATCAACCTGGCCCAG       c.13140
 D  A  V  N  K  G  L  V  D  K  I  M  V  D  R  I  N  L  A  Q         p.4380

          .         .         .         .         .         .       g.65044
 AAGGCCTTCTGCGGCTTCGAGGACCCACGCACCAAGACCAAGATGTCGGCCGCCCAGGCC       c.13200
 K  A  F  C  G  F  E  D  P  R  T  K  T  K  M  S  A  A  Q  A         p.4400

          .         .         .         .         .         .       g.65104
 CTGAAGAAGGGCTGGCTCTACTACGAGGCCGGCCAGCGCTTCCTGGAGGTGCAGTACCTG       c.13260
 L  K  K  G  W  L  Y  Y  E  A  G  Q  R  F  L  E  V  Q  Y  L         p.4420

          .         .         .         .         .         .       g.65164
 ACCGGCGGCTTGATCGAGCCCGACACGCCGGGCCGCGTGCCCCTGGACGAGGCCCTGCAG       c.13320
 T  G  G  L  I  E  P  D  T  P  G  R  V  P  L  D  E  A  L  Q         p.4440

          .         .         .         .         .         .       g.65224
 CGCGGCACGGTGGACGCCCGCACCGCACAGAAGCTGCGTGACGTGGGCGCCTACTCCAAG       c.13380
 R  G  T  V  D  A  R  T  A  Q  K  L  R  D  V  G  A  Y  S  K         p.4460

          .         .         .         .         .         .       g.65284
 TACCTCACCTGCCCTAAGACCAAGCTCAAGATCTCCTATAAGGACGCGCTGGACCGCAGC       c.13440
 Y  L  T  C  P  K  T  K  L  K  I  S  Y  K  D  A  L  D  R  S         p.4480

          .         .         .         .         .         .       g.65344
 ATGGTGGAGGAGGGCACGGGGCTGCGGCTGCTGGAGGCTGCCGCGCAGTCCACCAAGGGC       c.13500
 M  V  E  E  G  T  G  L  R  L  L  E  A  A  A  Q  S  T  K  G         p.4500

          .         .         .         .         .         .       g.65404
 TACTACAGCCCCTACAGCGTCAGCGGCTCCGGCTCTACCGCTGGCTCCCGCACCGGCTCG       c.13560
 Y  Y  S  P  Y  S  V  S  G  S  G  S  T  A  G  S  R  T  G  S         p.4520

          .         .         .         .         .         .       g.65464
 CGCACCGGCTCCCGGGCCGGCTCCCGCCGCGGCAGCTTTGACGCCACCGGCTCCGGCTTC       c.13620
 R  T  G  S  R  A  G  S  R  R  G  S  F  D  A  T  G  S  G  F         p.4540

          .         .         .         .         .         .       g.65524
 TCCATGACCTTCTCTTCATCCTCCTACTCCTCCTCGGGCTACGGCCGCCGCTACGCCTCG       c.13680
 S  M  T  F  S  S  S  S  Y  S  S  S  G  Y  G  R  R  Y  A  S         p.4560

          .         .         .         .                           g.65569
 GGGTCCTCGGCCTCCCTGGGGGGCCCTGAGTCTGCCGTGGCCTGA                      c.13725
 G  S  S  A  S  L  G  G  P  E  S  A  V  A  X                        p.4574

          .         .         .         .         .         .       g.65629
 ggctgcctgcgcccaccccgctctgcatgcggcccagcccggctcccaccgaggcgcggg       c.*60

          .         .         .         .         .         .       g.65689
 ggccgttttcaacgcttaaaggtgtcttcctcccaagtggtgcctaaagtttaaccaaaa       c.*120

          .         .         .         .         .         .       g.65749
 agaccagactaatatattaatatatatctgctgtccagacagcctgtatcttgggggaca       c.*180

          .         .         .         .         .         .       g.65809
 gggctggcccagccctgctggccgcctcaccccctcgggtctcctcactcccttctacct       c.*240

          .         .         .         .         .         .       g.65869
 gccactcacacagccaggtgccttggagggtcccaagctgggccccagcccaccctcctg       c.*300

          .         .         .         .         .         .       g.65929
 tcttcccagggtagcccgcctgccagtcctagctgcacagggcagctgggcccaaccctg       c.*360

          .         .         .         .         .         .       g.65989
 tctgtagagggccctggtgtttctagcactggcctgcacggtgggccttgctggggacgg       c.*420

          .         .         .         .         .         .       g.66049
 ggggccccagtcagcctctctcccagtctacccagagaagccccttccccatgggaagac       c.*480

          .         .         .         .         .         .       g.66109
 gaggccctcgggcccagcccccacagtgctgtctgatctgtgctttccagctcacccccc       c.*540

          .         .         .         .         .         .       g.66169
 acactcactcctgagacccctggcctccggcgtcagcctccagcctctgttcccctagta       c.*600

          .         .         .         .         .         .       g.66229
 agtgccttccatgtcggcctctaaccccaggccccgaggacccagacccagtggggaggc       c.*660

          .         .         .         .         .         .       g.66289
 ggacgttccagccggcatggctgggaactgcagacctgtcctcctggtgggtccaggggc       c.*720

          .         .         .         .         .         .       g.66349
 ccctccagcttgtggagccccacactggggtgccgcctgcccgtctctctcccatggagc       c.*780

          .         .         .         .         .         .       g.66409
 cccagccccctttgggcccagggacaccagccaggctctgtgctgaccctcctgttgcac       c.*840

          .         .         .         .         .         .       g.66469
 ccagccctggtctcagcagcgaccacccctgcctccaccctctgagctttgcatgttcca       c.*900

          .         .         .         .         .         .       g.66529
 ctaaccccgggcgggtggcaggtggaggtgtcaggctgctggcgcctctgcaagggcaga       c.*960

          .         .         .         .         .         .       g.66589
 acactaacctgaccgtgggcggggccttgcggtatccgcccccaataaaagcaattccaa       c.*1020

                                                                    g.66593
 cctt                                                               c.*1024

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10th nucleotide is indicated by a "." above the sequence. The Plectin protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift mutations, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.

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